-
Swainsonine is an
indolizidine alkaloid. It is a
potent inhibitor of
Golgi alpha-mannosidase II, an immunomodulator, and a
potential chemotherapy drug...
- that
McCandless might have been
poisoned by a
toxic alkaloid called swainsonine,
after eating sweet-vetch
seeds (Hedysarum
alpinum or
Hedysarum mackenzii)...
-
North America for any
plant that
produces swainsonine, an
alkaloid harmful to livestock. Worldwide,
swainsonine is
produced by a
small number of species...
-
toxic and it can be
hazardous to cattle; the
toxicity is
related to the
swainsonine produced by its endophytes, and to bioac****ulation of
selenium in the...
- such as
those found in the
United States containing the
neurotoxin swainsonine,
which causes "locoweed"
poisoning in animals. Some
astragalus species...
- are indolizidine,
which are
found in a
variety of
alkaloids such as
swainsonine.
Examples of some
simple substituted indolizines include 2ZEDMA, 1ZP2MA...
- of the
Eskimo potato,
which contained a
poisonous alkaloid,
possibly swainsonine (the
toxic chemical in locoweed) or
something similar. In
addition to...
- In
livestock alpha-mannosidosis is
caused by
chronic poisoning with
swainsonine from locoweed. Alpha-mannosidosis is a
lifelong multi-systemic progressive...
-
heterocycles have been
found in nature,
including deoxynojirimycin,
swainsonine,
australine and castanospermine. From
these natural templates many other...
-
produced as
metabolites by
fungi and bacteria. For instance,
Slaframine and
swainsonine were
identified in the
fungus Rhizoctonia leguminicola,
while Castanospermine...
