- into four groups: "true
subtilisins" (containing the
classical members), "high-alkaline
subtilisins", "intracellular
subtilisins", and "phylogenetically...
-
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is an
enzyme encoded by the PCSK9 gene in
humans on
chromosome 1. It is the 9th
member of the proprotein...
-
categories based on
their structure: chymotrypsin-like (trypsin-like) or
subtilisin-like. The
MEROPS protease classification system counts 16 superfamilies...
- (and
should not be
pronounced as such), but a
serine protease of the
subtilisin family (99.5%
identical with aprE). Rather, it is
named for the fact that...
-
Structures have been
determined for
several members of the
subtilisin family showing that
subtilisins exploit the same
catalytic triad as the chymotrypsins...
- substrate). It is
related to the
bacterial enzyme known as
subtilisin.
There are nine
subtilisin homologs in mammals; in
addition to
proprotein convertase...
-
family S8,
furin is a
subtilisin-like peptidase. The
protein encoded by this gene is an
enzyme that
belongs to the
subtilisin-like
proprotein convertase...
- sp,
subtilisin-like
pernisine from
Aeropyrum pernix,
alkaline protease from
Nocardiopsis sp,
nattokinase from B. subtilis,
engineered subtilisins from...
-
bacterial dysentery; its
efficacy (probably
attributable to the
antibiotic subtilisin from
Bacillus subtilis) was
anecdotally confirmed by
German soldiers in...
- a
fully human monoclonal antibody that
inhibits proprotein convertase subtilisin/kexin type 9 (PCSK9). PCSK9 is a
protein that
targets LDL
receptors for...
