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Streptozotocin or
streptozocin (INN, USP) (STZ) is a
naturally occurring alkylating antineoplastic agent that is
particularly toxic to the insulin-producing...
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Mitobronitol Nimustine Nitrosoureas Pipobroman Ranimustine Semustine Streptozotocin Temozolomide Thiotepa Treosulfan Triaziquone Triethylenemelamine Trofosfamide...
- are not
surgical candidates or who
otherwise have
inoperable tumours.
Streptozotocin is used in
islet cell
carcinomas which produce excessive insulin. Combination...
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extracted from the
fruit of S. torvum,
shows an
antidiabetic effect in
streptozotocin-induced
diabetic rats.
Cholinergic poisoning has been
reported as a...
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carmustine (BCNU),
lomustine (CCNU) and
semustine (MeCCNU),
fotemustine and
streptozotocin.
Tetrazines include dacarbazine,
mitozolomide and temozolomide. Aziridines...
-
Alloxan is, however,
toxic to the
liver and the
kidneys in high doses.
Streptozotocin Merck Index, 11th Edition, 281. Tipson, R. S. (1953). "Alloxantin dihydrate"...
- "Evaluation of the
glycemic effect of
Ceratonia siliqua pods (Carob) on a
streptozotocin-nicotinamide
induced diabetic rat model". PeerJ. 6: e4788. doi:10.7717/peerj...
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active fraction as anti-diabetic,
antihyperlipidemic and
antioxidant in
Streptozotocin-induced
diabetic rats".
Journal of Ethnopharmacology. 285: 114856. doi:10...
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mellitus can be
experimentally induced in vivo for
research purposes by
streptozotocin or alloxan,
which are
specifically toxic to beta cells.
Mouse and rat...
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models are
heavily represented in the literature. ICV
injection of
Streptozotocin has been used to
create a
metabolic model of Alzheimer's disease. This...