-
Altohyrtin A (
spongistatin 1,
cinachyrolide A) is a
polyether macrolide originally isolated from the
Okinawan marine sponge Hyrtios altum by Kobayashi...
- Bennett, Clay S.; Sakamoto,
Yasuharu (2003-03-01). "Total
Synthesis of (+)-
Spongistatin 1. An
Effective Second-Generation
Construction of an
Advanced EF Wittig...
- Bennett, Clay S.; Sakamoto,
Yasuharu (2003-03-01). "Total
Synthesis of (+)-
Spongistatin 1. An
Effective Second-Generation
Construction of an
Advanced EF Wittig...
-
synthesis of
complex molecules of
significant biological activity, such as
spongistatin 2 and
mandelalide A. It is
possible to form a bond
between two carbons...
-
examples including indanamycin, routiennocin,
avermectin B1a,
okadaic acid,
spongistatin, thapsigargin,
epothilone A,
antascomicin B,
bengazole A and rapamycin...
- products,
including (−)-Gloeosporone,
Epothilone A, the CD-Subunit of
spongistatins, and the C10-C20
Subunit of
rhizoxin A, The Keck
allylation has also...
- A. (1993). "Antineoplastic agents. 257.
Isolation and
structure of
spongistatin 1".
Journal of
Organic Chemistry. 58 (6): 1302–1304. doi:10.1021/jo00058a004...
-
activity including Daphniphyllum alkaloids, altohyrtin,
zaragozic acid,
spongistatins, and many others. He has also
developed novel methodology for organic...
- the
construction of
complex molecules, such as the
natural product spongistatins and
modern drugs.[page needed] It
remains to be seen
whether a particular...
