- the
spiro atom,
which is
usually a
quaternary carbon. An
example of a
spirocyclic compound is the
photochromic switch spiropyran. In fused/condensed bicyclic...
-
symmetric isomer of
spiroundecane is not. Some
spirocyclic compounds occur as
natural products. The
spirocyclic core is
usually prepared by
dialkylation of...
- Diaz JL,
Holenz J, Wünsch B (October 2008). "Thiophene
bioisosteres of
spirocyclic sigma receptor ligands. 1. N-substituted spiro[piperidine-4,4'-thieno[3...
- Stubbing,
Louise A. (2014), Cossy,
Janine (ed.), "Synthesis of 5,6- and 6,6-
Spirocyclic Compounds",
Synthesis of
Saturated Oxygenated Heterocycles I, vol. 35...
- C,
Mennini T, De
Amici M,
Gobbi M, et al. (November 2012). "A
novel spirocyclic tropanyl-Δ²-isoxazoline
derivative enhances citalopram and paroxetine...
- the most
challenging structural features of the
molecule are the C3
spirocyclic ring
juncture and the
adjacent prenyl-substituted carbon. Approaches...
-
Spiroheptane refers to
spirocyclic hydrocarbons with the
formula C(CH2)6. The
parent symmetrical member of this
group of
compounds is spiro[3.3]heptane...
- PMID 6708474. Sakamuri, Sukumar; et al. (2000). "Synthesis of
novel spirocyclic cocaine analogs using the
Suzuki coupling".
Tetrahedron Letters. 41 (13):...
- Brennan,
Megan (2009). "Asymmetric
Syntheses of
Oxindole and
Indole Spirocyclic Alkaloid Natural Products". Synthesis. 2009 (18): 3003–3025. doi:10.1055/s-0029-1216975...
-
Rearrangement and its
Application to the
Synthesis of a Difluoro-Substituted
Spirocyclic ORL-1 Antagonist". Angew. Chem. Int. Ed. 54 (49): 14898–902. doi:10.1002/anie...
