-
through a
carbon atom are the
usual focus of the
topic of
spirocycles.
Simple parent spirocycles include spiropentane, spirohexane, etc. up to spiroundecane...
-
reaction with thiols. It
forms acetals readily, a
prominent one
being the
spirocycle derived from pentaerythritol,
diallylidene pentaerythritol.
Acrolein parti****tes...
-
accordance with the
expected nucleophilicity of indoles, to give the
spirocycle 3.
After migration of the best
migrating group,
deprotonation gives the...
- core with an all-carbon
quaternary stereocenter at the
junction of the
spirocycle. Sigma-Aldrich Co., (−)-β-Chamigrene.
Retrieved on 4
October 2012. David...
-
Michael addition,
asymmetric multicomponent reactions for the
synthesis of
spirocycles,
asymmetric multicomponent reactions involving acyl
Strecker reactions...
- via an acid-catalyzed
reaction of p-cresol and acetone. The
resultant spirocycle is
halogenated with N-bromosuccinimide
followed by lithium-bromide exchange...
- diversity-oriented
synthesis platform,
based on newly-evolving
chemotypes such as
spirocycles and macrocycles. In 2016, she
became Senior Director of
Chemistry at...
- been able to be
isolated due to its instability,
whereas the boron-doped
spirocycle on the
right side
satisfies boron's octet,
forming a
zwitterion between...
-
Sukhen Karmakar,
Joseph Cherian, and
Mukund S. Chorghade. "Synthesis of
Spirocycles via Ring
Closing Metathesis of
Heterocycles Carrying Gem-Diallyl Substituents...
- addition-elimination
generates the
transient enone 1,
which rearranges to
spirocycle 2. (5)
Organolithiums can be emplo**** in a
similar role, but add in a...
