-
important phospholipid.
Sphingosine can be
phosphorylated in vivo via two kinases,
sphingosine kinase type 1 and
sphingosine kinase type 2. This leads...
-
Sphingosine-1-phosphate (S1P) is a
signaling sphingolipid, also
known as lysosphingolipid. It is also
referred to as a
bioactive lipid mediator. Sphingolipids...
- from the
precursor sphingolipid sphingosine.
Sphingolipid metabolites, such as ceramide,
sphingosine and
sphingosine-1-phosphate, are
lipid second messengers...
- enzymology, a
sphingosine cholinephosphotransferase (EC 2.7.8.10) is an
enzyme that
catalyzes the
chemical reaction CDP-choline +
sphingosine ⇌ {\displaystyle...
- enzymology, a
sphingosine beta-galactosyltransferase (EC 2.4.1.23) is an
enzyme that
catalyzes the
chemical reaction UDP-galactose +
sphingosine ⇌ {\displaystyle...
-
Sphingosine kinase 1 is an
enzyme that in
humans is
encoded by the SPHK1 gene.
Sphingosine kinase 1
phosphorylates sphingosine to
sphingosine-1-phosphate...
- In enzymology,
sphingosine N-acyltransferases (ceramide
synthases (CerS), EC 2.3.1.24) are
enzymes that
catalyze the
chemical reaction of
synthesis of...
- that
hydrolyze the
phosphocholine group from the
sphingosine backbone. Alternatively, this
sphingosine-derived
lipid (sphingolipid) can be synthesized...
-
Sphingosine-1-phosphate
receptor modulators are a
class of
drugs that
interact with S1P receptors, a
family of G protein-coupled
receptors involved in...
-
Sphingosine-1-phosphate
receptor 1 (S1P
receptor 1 or S1PR1), also
known as
endothelial differentiation gene 1 (EDG1) is a
protein that in
humans is encoded...
