-
important phospholipid.
Sphingosine can be
phosphorylated in vivo via two kinases,
sphingosine kinase type 1 and
sphingosine kinase type 2. This leads...
-
Sphingosine-1-phosphate (S1P) is a
signaling sphingolipid, also
known as lysosphingolipid. It is also
referred to as a
bioactive lipid mediator. Sphingolipids...
-
Ceramides are a
family of waxy
lipid molecules. A
ceramide is
composed of
sphingosine and a
fatty acid
joined by an
amide bond.
Ceramides are
found in high...
- medication, used for the
treatment of
multiple sclerosis.
Fingolimod is a
sphingosine-1-phosphate
receptor modulator,
which sequesters lymphocytes in lymph...
-
Sphingosine-1-phosphate
receptor 1 (S1P
receptor 1 or S1PR1), also
known as
endothelial differentiation gene 1 (EDG1) is a
protein that in
humans is encoded...
- The
sphingosine-1-phosphate
receptors are a
class of G protein-coupled
receptors that are
targets of the
lipid signalling molecule Sphingosine-1-phosphate...
- from the
precursor sphingolipid sphingosine.
Sphingolipid metabolites, such as ceramide,
sphingosine and
sphingosine-1-phosphate, are
lipid second messengers...
-
coordinated for this purpose.
Sphingosine kinase (SK) is a
lipid kinase that
catalyzes the
conversion of
sphingosine to
sphingosine-1-phosphate (S1P). Sphingolipids...
- enzymology, a
sphingosine cholinephosphotransferase (EC 2.7.8.10) is an
enzyme that
catalyzes the
chemical reaction CDP-choline +
sphingosine ⇌ {\displaystyle...
-
sphingoid bases,
which are a set of
aliphatic amino alcohols that
includes sphingosine. They were
discovered in
brain extracts in the 1870s and were
named after...
