-
depending on the pH in
which their enzymatic activity is optimal. Acid
sphingomyelinases' (aSMases)
enzymatic activity can be
influenced by drugs, lipids,...
- and
Staphylococcus aureus.
Using the
sequences of
these bacterial sphingomyelinases in
homology searches ultimately led to the
identification of the yeast...
- Niemann–Pick
disease (NP), also
known as acid
sphingomyelinase deficiency, is a
group of rare
genetic diseases of
varying severity.
These are inherited...
- of cholesterol, phospholipids, and of lipid-soluble
vitamins and
sphingomyelinases; however,
these are
usually treated separately from "conventional"...
-
classified as
phospholipases D or
lipophosphodiesterase II EC 3.1.4.4.
Sphingomyelinases D are
produced by some
spiders in
their venoms,
specifically the brown...
-
inhibitors of acid
sphingomyelinase, or FIASMA, is a
large group of
pharmacological compounds inhibiting the
enzyme acid
sphingomyelinase (ASM, EC 3.1.4.12)...
-
initiating many
universal signaling pathways. It is
hydrolyzed by
sphingomyelinases (sphingomyelin
specific type-C phospholipases). The phosphocholine...
-
Stoffel W (November 1999). "Functional
analysis of acid and
neutral sphingomyelinases in
vitro and in vivo".
Chemistry and
Physics of Lipids. 102 (1–2):...
-
Priscila Hess; Berg,
Carmen W. van den; Tambourgi,
Denise V. (2020). "
Sphingomyelinases D From
Loxosceles Spider Venoms and Cell Membranes:
Action on Lipid...
-
treatment of non-central
nervous system (CNS)
manifestations of acid
sphingomyelinase deficiency type A/B or type B. The most
common side
events include...
