-
Sphingomyelin phosphodiesterase (EC 3.1.4.12, also
known as
neutral sphingomyelinase,
sphingomyelinase, or SMase;
systematic name
sphingomyelin cholinephosphohydrolase)...
- Acid
sphingomyelinase is one of the
enzymes that make up the
sphingomyelinase (SMase) family,
responsible for
catalyzing the
breakdown of sphingomyelin...
- Niemann–Pick
disease (NP), also
known as acid
sphingomyelinase deficiency, is a
group of rare
genetic diseases of
varying severity.
These are inherited...
- live for one and a half to two years. All
genera are able to
produce sphingomyelinase D or a
related tissue-destroying substance. It is
unique to the family...
-
treatment of non-central
nervous system (CNS)
manifestations of acid
sphingomyelinase deficiency type A/B or type B. The most
common side
events include...
-
Sphingomyelin phosphodiesterase D (EC 3.1.4.41,
sphingomyelinase D) is an
enzyme of the
sphingomyelin phosphodiesterase family with
systematic name sphingomyelin...
-
Sphingomyelin phosphodiesterase 1 (SMPD1), also
known as acid
sphingomyelinase (ASM), is an
enzyme that in
humans is
encoded by the SMPD1 gene. Sphingomyelin...
- therapy.
Benzatropine also acts as a
functional inhibitor of acid
sphingomyelinase (FIASMA). In
veterinary medicine,
benzatropine is used to
treat priapism...
-
initiating many
universal signaling pathways. It is
hydrolyzed by
sphingomyelinases (sphingomyelin
specific type-C phospholipases). The phosphocholine...
-
toxin produced by
Staphylococcus aureus. It is a form of
sphingomyelinase called sphingomyelinase C. This
enzyme is
toxic to a
variety of cells, including...
