-
Allegood JC, Wang E,
Merrill AH Jr,
Schwartz GK (2009). "Safingol (L-threo-
sphinganine)
induces autophagy in
solid tumor cells through inhibition of PKC and...
-
Chemotherapeutic agents Fas
ligand Endotoxin Homocysteine Heat
Hydroxypalmitoyl Sphinganine Gamma interferon Ionizing radiation Matrix metalloproteinases Niacinamide...
-
Dehydrosphingosine is then
reduced by
NADPH to
dihydrosphingosine (
sphinganine),
acylated to
dihydroceramide and
finally oxidized by FAD to ceramide...
- The
enzyme sphinganine-1-phosphate
aldolase (EC 4.1.2.27)
catalyzes the
chemical reaction sphinganine 1-phosphate ⇌ {\displaystyle \rightleftharpoons }...
-
Sphinganine C4-monooxygenase (EC 1.14.13.169,
sphingolipid C4-hydroxylase, SUR2 (gene), SBH1 (gene), SBH2 (gene)) is an
enzyme with
systematic name sphinganine...
-
forming 3-ketosphinganine (Fig. 1). This
product is then
reduced to
sphinganine, also
known as
dihydrosphingosine (dihydro-Sph; 2-amino-1,3-dihydroxy-octadecane)...
-
sphinganine,
sphingosine and
their 1-phosphate
metabolites and in
decreased concentrations of
complex sphingolipids. The ac****ulation of
sphinganine and...
-
specifically known as
phytosphingosine and
dihydrosphingosine (also
known as
sphinganine,
although this term is less common), are
mainly C18 compounds, with somewhat...
- Palmitoyl-CoA
Serine 3-Ketosphinganine (dehydrosphingosine)
Dihydrosphingosine (
sphinganine)
Dihydroceramide Ceramide Sphingosine See also: Receptor/signaling modulators...
- reaction,
serine is
decarboxylated and
combined with palmitoyl-CoA to form
sphinganine,
which is
combined with a
fatty acyl-CoA to form dihydroceramide. This...
