-
working on
these molecules (by convention,
Siglecs are
always capitalised.)
Several additional Siglecs (
Siglecs 5–12) have been
identified in
humans that...
- tail
compared to most CD33-****ociated
siglecs. Subsequently, a
longer form of
Siglec-8,
initially termed Siglec-8L, that
contains 499
amino acid residues...
-
these osteoblasts can
worsen tumors in two ways. First, they can
induce SiglecFhigh-expressing
neutrophil formation that in turn
promotes lung
tumor growth...
- (Heat-stable antigen).
SIGLECs are
members of the
immunoglobulin superfamily that are
expressed on the cell surface. Most
SIGLECs have 1 or more cytoplasmic...
-
motif is
critical for the
inhibitory signaling mediated by
Siglecs-7 and -9, CD33-related
Siglecs expressed on
human monocytes and NK cells". J. Immunol....
- neutrophils, macrophages,
dendritic cells and
activated T-cells (SIGLEC9).
SIGLECs 7 and 9
suppress the
immune function of
these cells by
binding to terminal...
- its N-terminus. It is a
member of the
immunoglobulin superfamily and the
SIGLEC family. CD22
functions as an
inhibitory receptor for B cell
receptor (BCR)...
-
MedlinePlus Overview bonecancer Wang Y, Zhan X, et al. (January 22, 2024). "
Siglec-15/sialic acid axis as a
central glyco-immune
checkpoint in
breast cancer...
-
mammalian glycan-binding
proteins (GBPs): C-type lectin, galectin, and
SIGLEC immune receptors that bind carbohydrates: CD1, T cell receptor, and anti-carbohydrate...
- OAS3, RSAD2 and
sialoadhesin genes (the gene for
sialoadhesin is
termed SIGLEC-1). The
abnormal presence of
these mRNAs in
tissues is
sometimes termed...
