-
Siglecs (Sialic acid-binding immunoglobulin-type lectins) are cell
surface proteins that bind
sialic acid. They are
found primarily on the
surface of...
- They
found that 9 of the 12
marketed Siglec-Fc
reagents bind to HeLa cells, and two of which,
Siglec-11 and
Siglec-14, had
binding that was vulnerable...
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Sialoadhesin (
SIGLEC-1) is a cell
adhesion molecule found on the
surface of
various immune cells. It is
found in
especially high
amounts on macrophages...
- of the SIGLEC9 gene.
Within the
siglec family of
transmembrane proteins,
Siglec-8
belongs to the CD33-related
siglec subfamily, a
subfamily that has undergone...
- CD33 or
Siglec-3 (sialic acid
binding Ig-like
lectin 3, SIGLEC3,
SIGLEC-3, gp67, p67) is a
transmembrane receptor expressed on
cells of
myeloid lineage...
-
Crocker PR (Dec 1999). "Identification and
characterization of a
novel siglec,
siglec-7,
expressed by
human natural killer cells and monocytes". J Biol Chem...
- the SIGLEC10 gene.
Siglec-G is
often referred to as the
murine paralog of
human Siglec-10 Like most but not all
other Siglecs,
Siglec-10
bears an ITIM (Immunoreceptor...
-
sixth member of the
SIGLEC family of
receptors to be identified. The
protein has also been
given the CD
designation CD327.
Siglec-6 was
first found to...
- a humanized,
nonfucosylated IgG1
monoclonal antibody that
targets Siglec-8.
Siglec-8 is an
inhibitory receptor present on
eosinophils and mast cells,...
-
Sialic acid
binding Ig-like
lectin 15 (
Siglec-15) is a
protein that in
humans is
encoded by the SIGLEC15 gene.
Siglec-15 is
predominately expressed on osteoclasts...
