-
mechanism is
dependent on the
presence of a
sialylated glycan at
position CH2-84.4 of IgG. Specifically, de-
sialylated preparations of
immunoglobulin lose their...
- used
primarily in the
management of
pancreatic cancer. CA19-9 is the
sialylated form of
Lewis antigenA. It is a
tetrasaccharide with the sequence...
-
rotaviruses (Reoviridae) and
influenza viruses (Orthomyxoviridae) can use host-
sialylated structures for
binding to
their target host cell.
Sialic acids provide...
-
levels on NK cell surfaces. It is used in cell-cell contacts,
binding to
sialylated glycans on
target cells leading to
inhibition of NK cell-dependent killing...
- of
polyomaviruses to host
cells is
mediated by the
binding of VP1 to
sialylated glycans on the cell surface. In some
particular viruses,
additional cell-surface...
-
reported ligands for E-selectin is the
sialylated Lewis X
antigen (SLex). Eosinophils, like neutrophils, use
sialylated, protease-resistant
structures to bind...
- L-selectin
belongs to the
selectin family of proteins,
which recognize sialylated carbohydrate groups containing a
Sialyl LewisX (sLeX) determinant. L-selectin...
- proteins; as C1-inhibitor is
particularly heavily glycosylated, this
sialylated recombinant form
would have a
short circulatory life (the carbohydrates...
- can lead to
increased activity in
other vital pathways of
cancer cells.
Sialylated, O-glycosylated
glycoforms of
podocalyxin expressed by
colon carcinoma...
-
cartilages and
other body structures, some
types of mucopolysaccharides,
sialylated glycocalyx of
cells etc. For many of
these targets it is one of the most...
