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Sialyl LewisX (sLeX), also
known as
cluster of
differentiation 15s (CD15s) or stage-specific
embryonic antigen 1 (SSEA-1), is a
tetrasaccharide carbohydrate...
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Carbohydrate antigen 19-9 (CA19-9), also
known as
sialyl-LewisA, is a
tetrasaccharide which is
usually attached to O-glycans on the
surface of cells. It...
-
Metastatic breast cancer, also
referred to as metastases,
advanced breast cancer,
secondary tumors,
secondaries or
stage IV
breast cancer, is a
stage of...
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Sialyltransferases are
enzymes that
transfer sialic acid to
nascent oligosaccharide. Each
sialyltransferase is
specific for a
particular sugar substrate...
- organism. SabA (coded for by the sabA gene)
binds to
increased levels of
sialyl-Lewis X
antigen expressed on
gastric mucosa. The
outer membrane contains...
-
cells and
interact with T
cells as part of the
adaptive immune response.
sialyl Lewis X
antigen on the
surface of leukocytes. H
antigen of the ABO blood...
- to bind to
inward sialyl Lewis molecules ****her up
along the PSGL-1 chain,
increasing overall binding affinity—if the selectin-
sialyl Lewis bond breaks...
-
anhydrosialidase (EC 4.2.2.15)
catalyzes the
following process:
Elimination of α-
sialyl groups in N-acetylneuraminic acid glycosides,
releasing 2,7-anhydro-α-N-acetylneuraminate...
- of proteins,
which recognize sialylated carbohydrate groups containing a
Sialyl LewisX (sLeX) determinant. L-selectin
plays an
important role in both the...
- peptide/proteins (also
called Tn antigen) with an α2-6
linkage to
produce the
sialyl-Tn antigen. It has been
shown that the
enzyme prefers threonine over serine...
