-
Small interfering RNA (
siRNA),
sometimes known as
short interfering RNA or
silencing RNA, is a
class of double-stranded non-coding
RNA molecules, typically...
-
ribonucleic acid (
RNA) molecules, micro
RNA (mi
RNA) and
small interfering RNA (
siRNA), are
central to
components to the RNAi pathway. Once m
RNA is degraded,...
-
transfer RNA (t
RNA), micro
RNA (mi
RNA),
small interfering RNA (
siRNA),
small nucleolar RNA (sno
RNAs), Piwi-interacting
RNA (pi
RNA), t
RNA-derived
small RNA (tsRNA)...
- levels.
Using single-stranded
RNA (ss
RNA) fragments, such as micro
RNA (mi
RNA), or double-stranded
small interfering RNA (
siRNA), the
complex functions as...
-
interfering RNA (
siRNA) and
micro RNA (mi
RNA) to
prevent m
RNA translation and/or
degrade m
RNA. However,
RNA aptamers are short,
single stranded RNA molecules...
- "Sequence-specific
inhibition of micro
RNA- and
siRNA-induced
RNA silencing".
RNA. 10 (3): 544–50. doi:10.1261/
rna.5235104. PMC 1370948. PMID 14970398....
- the
RNA-induced
silencing complex or RISC. This
complex contains an
endonuclease that
cleaves perfectly complementary messages to
which the
siRNA binds...
- trans- and infection.
Genetic material (such as
supercoiled plasmid DNA or
siRNA constructs), may be transfected.
Transfection of
animal cells typically...
- of
siRNA to
target luciferase or eGFP m
RNA reporters. In
another study, TAT-
siRNA conjugate through a
stable thiomaleimide linkage at 3'-end of
siRNA was...
- of
small RNA have
currently been identified, namely:
small interfering RNA (
siRNA), micro
RNA (mi
RNA), and piwi-interacting
RNA (pi
RNA).
siRNAs act in the...