Definition of Sheddase. Meaning of Sheddase. Synonyms of Sheddase

- Sheddases are membrane-bound enzymes that cleave extracellular portions of transmembrane proteins, releasing the soluble ectodomains from the cell surface...
- interactions. Those ADAMs which are active proteases are classified as sheddases because they cut off or shed extracellular portions of transmembrane proteins...
- examples of enzymes that can induce shedding of the glycocalyx and these sheddases can therefor contribute to degradation of the glycocalyx layer in several...
- of body parts Desquamation, pathologic or non-pathologic skin shedding Sheddase and Ectodomain shedding Shedding game, a family of card games where the...
- unique structure, possessing both potential adhesion and protease domains. Sheddase, a generic name for the ADAM metallopeptidase, functions primarily to cleave...
- loss of glycocalyx and is therefore considered as a potential endogenous sheddase. However, plasma hyaluronidase activity is decreased in experimental as...
- Aderbasib (codenamed INCB7839) is a sheddase inhibitor that may suppress tumor cell proliferation. Acting on multiple receptor classes and subclasses,...
- transmembrane domain by another enzyme known as ADAM17 a member of the sheddase enzyme family, during the protective phase of RAAS, the Renin–Angiotensin–Aldosterone...
- thought to function as intramembrane serine proteases. RHBDL2 functions as a sheddase and is localized to the plasma membrane. Known substrates of RHBDL2 include...
- cellular membrane. The molecule can also keep its full-length form as long as it is protected from the action of the sheddase (furin) by lipid rafts....