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Sepiapterin, also
known as 2-amino-6-[(2S)-2-hydroxypropanoyl]-7,8-dihydro-1H-pteridin-4-one, is a
member of the
pteridine class of
organic chemicals...
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Sepiapterin reductase is an
enzyme that in
humans is
encoded by the SPR gene.
Sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase; EC 1.1...
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Escherichia coli can also
convert 6-pyruvoyl-5,6,7,8-tetrahydropterin and
sepiapterin to 6-carboxy-5,6,7,8-tetrahydropterin.
Cicmil N, Shi L (February 2008)...
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Sepiapterin reductase deficiency is an
inherited pediatric disorder characterized by
movement problems, and most
commonly displa**** as a
pattern of involuntary...
- In enzymology, a
sepiapterin deaminase (EC 3.5.4.24) is an
enzyme that
catalyzes the
chemical reaction sepiapterin + H2O ⇌ {\displaystyle \rightleftharpoons...
- also
appears to
inhibit the cystine-glutamate antiporter, as well as
sepiapterin reductase. It is a
codrug which is a
combination of
sulfapyridine and...
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recessive Segawa syndrome) 6-Pyruvoyltetrahydropterin
synthase deficiency Sepiapterin reductase deficiency Dihydropteridine reductase deficiency The precursor...
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cyclohydrolase I (GTPCH), 6-pyruvoyltetrahydropterin
synthase (PTPS), and
sepiapterin reductase (SR). BH4 can be
oxidized by one or two
electron reactions...
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processor released in 2023 SPR, a
human gene
which codes for the
enzyme sepiapterin reductase Specialist registrar (SpR),
physician position in
Ireland and...
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Nagatsu T (August 1991). "Cloning and
sequencing of cDNA
encoding human sepiapterin reductase--an
enzyme involved in
tetrahydrobiopterin biosynthesis". Biochemical...
