Definition of Separase. Meaning of Separase. Synonyms of Separase

- Separase, also known as separin, is a cysteine protease responsible for triggering anaphase by hydrolysing cohesin, which is the protein responsible for...
- securin and separase are well conserved proteins (Figure 1). Note that separase cannot function without initially forming the securin-separase complex. This...
- and is under balanced bipolar tension. Sister chromatids require active separase to hydrolyze the cohesin that bind them together prior to progression to...
- is a protein which inhibits a protease known as separase. The destruction of securin unleashes separase which then breaks down cohesin, a protein responsible...
- protease partner, separase. Separase bound to securin remains inhibited; however, when inhibition is relieved, activated separase cleaves the cohesin...
- can be attributed to the inactivation of topoisomerase II, condensin, or separase. Meiotic nondisjunction has been well studied in Saccharomyces cerevisiae...
- break down securin. The latter is a protein whose function is to inhibit separase, which in turn cuts the cohesins, the protein composite responsible for...
- broken down is securin which through its breakdown releases the enzyme separase that cleaves the cohesin rings holding together the sister chromatids thereby...
- APC/C are securin and S and M cyclins. Securin releases separase, a protease, when degraded. Separase then triggers the cleavage of cohesin, the protein complex...
- are pulled apart from each other. The homologs are cleaved by the enzyme separase to release the cohesin that held the homologous chromosome arms together...