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Semagacestat (LY-450139) was a
candidate drug for a
causal therapy against Alzheimer's disease. It was
originally developed by Eli
Lilly and Elan, and...
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azepine ring.
Examples include:
Benazepril Fenoldopam GSK-189,254
Ivabradine Semagacestat Varenicline Trepipam SKF-38,393
Benzodiazepine Dibenzazepine v t e...
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seltraposin (INN)
selumetinib (USAN)
selurampanel (INN)
selvacovatein (INN)
semagacestat (USAN, INN)
semaglutide (INN)
sematilide (INN)
semduramicin (INN) Semicid...
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patients with Alzheimer’s disease. An
example of such a
molecule is
semagacestat. Elan also
studied other neurodegenerative diseases, such as Parkinson's...
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disease (AD). The drug
semagacestat in
contrast to imatinib,
works by
directly inhibiting the γ-secretase.
While semagacestat reduces β-amyloid plaque...
- (chemical), a γ-secretase
inhibitor Nirogacestat, a γ-secretase
inhibitor Semagacestat, a γ-secretase
inhibitor Bai, Xiao-chen; Yan, Chuangye; Yang, Guang****;...
