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Seltorexant, also
known by its
developmental code
names MIN-202 and JNJ-42847922, is an
orexin antagonist medication which is
under development for the...
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previously for
anxiety disorders, up to
phase 2 – half-life 3–7
hours Seltorexant (MIN-202, JNJ-42847922, JNJ-922) –
selective OX2
antagonist –
under development...
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cleared in the
earlier phases of elimination. The
investigational agents seltorexant and vornorexant,
which are
still in
clinical trials, have comparatively...
- (SMD 0.07),
orexin receptor antagonists (daridorexant, lemborexant,
seltorexant, suvorexant) (SMDs 0.23 to 0.44), and
melatonin receptor agonists (melatonin...
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Filorexant GSK-649868 (SB-649868) JNJ-10397049
Lemborexant MK-1064 MK-3697 MK-8133
Seltorexant Suvorexant TCS-1102 TCS-OX2-29
Vornorexant (ORN-0829, TS-142)...
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Filorexant GSK-649868 (SB-649868) JNJ-10397049
Lemborexant MK-1064 MK-3697 MK-8133
Seltorexant Suvorexant TCS-1102 TCS-OX2-29
Vornorexant (ORN-0829, TS-142)...
-
Zuranolone (SAGE-217) –
GABAA receptor positive allosteric modulator [3]
Seltorexant (MIN-202, JNJ,42847922, JNJ-922) –
selective OX2
receptor antagonist...
-
Filorexant GSK-649868 (SB-649868) JNJ-10397049
Lemborexant MK-1064 MK-3697 MK-8133
Seltorexant Suvorexant TCS-1102 TCS-OX2-29
Vornorexant (ORN-0829, TS-142)...
-
Filorexant GSK-649868 (SB-649868) JNJ-10397049
Lemborexant MK-1064 MK-3697 MK-8133
Seltorexant Suvorexant TCS-1102 TCS-OX2-29
Vornorexant (ORN-0829, TS-142)...
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Filorexant GSK-649868 (SB-649868) JNJ-10397049
Lemborexant MK-1064 MK-3697 MK-8133
Seltorexant Suvorexant TCS-1102 TCS-OX2-29
Vornorexant (ORN-0829, TS-142)...
