Definition of Securin. Meaning of Securin. Synonyms of Securin

Here you will find one or more explanations in English for the word Securin. Also in the bottom left of the page several parts of wikipedia pages related to the word Securin and, of course, Securin synonyms and on the right images related to the word Securin.

Definition of Securin

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Meaning of Securin from wikipedia

- Securin is a protein involved in control of the metaphase-anaphase transition and anaphase onset. Following bi-orientation of chromosome pairs and inactivation...
- called securin for destruction by ubiquitylating it. Securin is a protein which inhibits a protease known as separase. The destruction of securin unleashes...
- APC/C), a ubiquitin ligase which targets securin and cyclin B for degradation via the proteosome. As long as securin and cyclin B remain active, separase...
- The three major targets for degradation by the APC/C are securin and S and M cyclins. Securin releases separase, a protease, when degraded. Separase then...
- 2021, structures of human separase were determined in complex with either securin or CDK1-cyclin B1-CKS1 using cryo-EM by scientists of the University of...
- protein, securin, for destruction. Securin destruction liberates and activates its bound protease partner, separase. Separase bound to securin remains...
- degrade cyclin B, which harbors a D-box (destruction box), and to break down securin. The latter is a protein whose function is to inhibit separase, which in...
- the APC/C core. When securin, Cdc20, and E2 are all bound to APC/C E2 ubiquitinates securin and selectively degrades it. Securin degradation releases...
- " Up-regulated genes in the signature include: SNRPF, HNRPAB, DHPS and securin. Actin, myosin and MHC class II down-regulation was also ****ociated with...
- metaphase-anaphase transition. One of these proteins that is broken down is securin which through its breakdown releases the enzyme separase that cleaves the...