Definition of Secretases. Meaning of Secretases. Synonyms of Secretases

- ADAM10, have been identified as possessing alpha-secretase activity. Upon cleavage by alpha secretases, APP releases its extracellular domain - a fragment...
- Secretases are enzymes that "snip" pieces off a longer protein that is embedded in the cell membrane. Among other roles in the cell, secretases act on...
- Gamma secretase is a multi-subunit protease complex, an integral membrane protein, that cleaves single-p**** transmembrane proteins at residues within...
- Beta-secretase 1, also known as beta-site amyloid precursor protein cleaving enzyme 1, beta-site APP cleaving enzyme 1 (BACE1), membrane-****ociated aspartic...
- proteolytic enzymes α-, β- and γ-secretase; Aβ protein is generated by successive action of the β and γ secretases. The γ secretase, which produces the C-terminal...
- Beta-secretase is a protein family that includes in humans Beta-secretase 1 and Beta-secretase 2. Tallon C, Farah MH (October 2017). "Beta secretase activity...
- Beta-secretase 2 (EC 3.4.23.45, also known as Memapsin-1) is an enzyme that cleaves Glu-Val-Asn-Leu-|-Asp-Ala-Glu-Phe in the Swedish variant of Alzheimer's...
- the gamma secretase complex along with the catalytic subunit presenilin and the regulatory subunits nicastrin and PEN-2. The gamma-secretase complex is...
- beta secretases and gamma secretase. Presenilin is the sub-component of gamma secretase that is responsible for the cutting of APP. Gamma secretase can...
- survival, and post-injury repair. In Alzheimer's disease, gamma secretase and beta secretase act together in a proteolytic process which causes APP to be...