Definition of Secretase. Meaning of Secretase. Synonyms of Secretase

- Gamma secretase is a multi-subunit protease complex, an integral membrane protein, that cleaves single-p**** transmembrane proteins at residues within...
- Beta-secretase 1, also known as beta-site amyloid precursor protein cleaving enzyme 1, beta-site APP cleaving enzyme 1 (BACE1), membrane-****ociated aspartic...
- Secretases are enzymes that "snip" pieces off a longer protein that is embedded in the cell membrane. Among other roles in the cell, secretases act on...
- processed by beta secretase and gamma secretase. The alpha-secretase pathway is the predominant APP processing pathway. Thus, alpha-secretase cleavage precludes...
- Beta-secretase 2 (EC 3.4.23.45, also known as Memapsin-1) is an enzyme that cleaves Glu-Val-Asn-Leu-|-Asp-Ala-Glu-Phe in the Swedish variant of Alzheimer's...
- Beta-secretase is a protein family that includes in humans Beta-secretase 1 and Beta-secretase 2. Tallon C, Farah MH (October 2017). "Beta secretase activity...
- the gamma secretase complex along with the catalytic subunit presenilin and the regulatory subunits nicastrin and PEN-2. The gamma-secretase complex is...
- astrocytes. Following cleavage by β-secretase, APP is cleaved by a membrane-bound protein complex called γ-secretase to generate Aβ. Presenilins 1 and 2...
- transmembrane proteins which constitute the catalytic subunits of the gamma-secretase intramembrane protease protein complex. They were first identified in...
- APP is cleaved into smaller fragments by enzymes such as gamma secretase and beta secretase. One of these fragments gives rise to fibrils of amyloid beta...