- humans,
phospholipid scramblases (PLSCRs)
constitute a
family of five
homologous proteins that are
named as hPLSCR1–hPLSCR5.
Scramblases are
members of the...
-
hydrolysis and are
either P4-ATPases or ATP-Binding C****ette transporters.
Scramblases are energy-independent and
transport lipids in both directions. In organisms...
-
gradient in an energy-dependent manner. Additionally,
there are also "
scramblase"
proteins that move
phospholipids in both
directions at the same time...
- HM,
Baldridge RD, Xu P,
Graham TR (January 2015). "Role of flippases,
scramblases and
transfer proteins in
phosphatidylserine subcellular distribution"...
-
Phospholipid scramblase 1 (PL
scramblase 1) is an
enzyme that in
humans is
encoded by the PLSCR1 gene. PLSCR1 has been
shown to
interact with: CPSF6,...
-
redistributed during apoptosis to the
extracellular surface by a
protein known as
scramblase.
These molecules mark the cell for
phagocytosis by
cells possessing the...
-
transmembrane protein complexes such as pores,
channels and gates.
Flippases and
scramblases concentrate phosphatidyl serine,
which carries a
negative charge, on...
-
which place them
exclusively on the
cytosolic side and the
activation of
scramblases,
which scramble the
orientation of the phospholipids.
After this occurs...
- to
become negatively charged. One of the
signaling pathways turns on
scramblase,
which moves negatively charged phospholipids from the
inner to the outer...
- "Calcium
binding studies of
peptides of
human phospholipid scramblases 1 to 4
suggest that
scramblases are new
class of
calcium binding proteins in the cell"...
