-
Scoulerine, also
known as
discretamine and aequaline, is a
benzylisoquinoline alkaloid (BIA) that is
derived directly from (S)-reticuline
through the action...
- (EC 1.14.21.2) is an
enzyme that
catalyzes the
chemical reaction (S)-
scoulerine +
NADPH + H+ + O2 ⇌ {\displaystyle \rightleftharpoons } (S)-cheilanthifoline...
- a (S)-
scoulerine 9-O-methyltransferase (EC 2.1.1.117) is an
enzyme that
catalyzes the
chemical reaction S-adenosyl-L-methionine + (S)-
scoulerine ⇌ {\displaystyle...
-
victims were
attributable to the
effects on the CNS of the
alkaloids scoulerine (which can act as a
GABAA receptor agonist) and
corydine which can evoke...
- of five
enzymatic transformations: 1)
berberine bridge enzyme to (S)-
Scoulerine; 2) (S)-cheilanthifoline synthase/CYP719A25 to (S)-Cheilanthifoline; 3) ...
-
chemical compounds found in
plants in this
genus include alkaloids such as
scoulerine, erysodin,
erysovin (namely in E. flabelliformis), and the ****tive anxiolytic...
- not
encoded by the cluster,
forms the
fused four-ring
structure in (S)-
scoulerine. BBE uses O2 as an
oxidant and is
aided by
cofactor flavin adenine dinucleotide...
-
codeinone (as in the
biosynthesis of morphine),
reticuline is
converted to
scoulerine via
berberine bridge enzyme (BBE). As such, this is the
commitment step...
- the
responsible of
catalyzing the
conversion of (S)-reticuline to (S)-
scoulerine. This
conversion is made by an
oxidative ring
closure reaction. The product...
- (S)-reticuline.
Reticuline oxidase uses (S)-reticuline and O2 to
produce (S)-
scoulerine and H2O2.
Salutaridine synthase uses (R)-reticuline, NADPH, H+, and O2...
