- rRNA
endonuclease (EC 3.1.27.10, alpha-
sarcin) is an
enzyme that
catalyses the
hydrolysis of the
phosphodiester linkage between guanosine and adenosine...
-
phenomena such as
tumour transformation or a
viral infection. This is why α-
sarcin, the most
representative member of the group, was
originally discovered...
- (RIPs),
similar to
Sarcin or Ricin.
These toxins depurinate a
conserved adenine site in
eukaryotic 28s
ribosomal RNA
called the
Sarcin-Ricin loop by cleaving...
-
found in
eukaryotic ribosomes. The sequence, 5'-AGUACGAGAGGA-3',
termed the
sarcin-ricin loop, is
important in
binding elongation factors during protein synthesis...
- erythromycin, kasugamycin, micrococcin, paromomycin, linezolid, alpha-
sarcin, spectinomycin, streptomycin, and thiostrepton. rRNA have been
shown to...
- PMID 3167211.
Terao K,
Uchiumi T, Endo Y,
Ogata K (June 1988). "Ricin and alpha-
sarcin alter the
conformation of 60S
ribosomal subunits at
neighboring but different...
- the C-loop, the docking-elbow, kink-turns (k-turn), the right-angle, the
sarcin/ricin
loops (also
called bulged-G motifs), the twist-up
motif and the UAA/GAN...
- of two
smaller regions of 23S
ribosomal RNA
called the L11
stalk and the
sarcin-ricin loop (SRL). As a
highly conserved rRNA loop in evolution, the SRL...
- asel-lus/-la domĭn-us domĭn-ulus gemĭn-us gemel-lus fēmĭn-a fēmel-la
sarcĭn-a
sarcĭn-ula fiscĭn-a fiscel-la fuscĭn-a fuscĭn-ula pāgĭn-a pāgel-la pāgĭn-a...
- that
ribosome to parti****te in
protein synthesis. The
fungal toxin alpha-
sarcin cuts the
ribosomal RNA at the
adjacent base, also
causing protein synthesis...
