Definition of Saposins. Meaning of Saposins. Synonyms of Saposins

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Definition of Saposins

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Meaning of Saposins from wikipedia

- conserved glycoprotein is a precursor for 4 cleavage products: saposins A, B, C, and D. Saposin is an acronym for Sphingolipid Activator PrO[S]teINs. Each...
- The saposin domains refers to two evolutionally-conserved protein domains found in saposin and related proteins (SAPLIP). Saposins are small lysosomal...
- of the prosaposin gene leads to a complete deficiency of prosaposin and saposins, and is ****ociated with a complex sphingolipidosis dominated by lactosylceramide...
- that codes for saposin is called prosaposin. It is a precursor for four cleavage products, the saposins A, B, C, and D. The four saposin domains most likely...
- requires the activating protein Saposin C as well as negatively charged lipids for maximal catalytic activity. The role of Saposin C is not known; however, it...
- surfactant-****ociated protein B (pulmonary surfactant regulation) and the saposins (sphingolipid degradation) of which SAPLIPs are named after. Specific to...
- of the lung. Humans and animals born with a congenital absence of the saposin family SP-B experience intractable respiratory failure whereas those born...
- Deficiency". GeneReviews, 2006 Kishimoto Y, Hiraiwa M, O'Brien JS (Sep 1992). "Saposins: structure, function, distribution, and molecular genetics". J. Lipid Res...
- sphingomyelinase, surfactant protein B, and the 4 sphingolipid activator proteins (saposins). The larger subunit, of 50 kDa, contains the active site serine and the...
- galactosylceramidase. In rare cases, it may be caused by a lack of active saposin A (a derivative of prosaposin). The buildup of unmetabolized lipids adversely...