Definition of Saposin. Meaning of Saposin. Synonyms of Saposin

- conserved glycoprotein is a precursor for 4 cleavage products: saposins A, B, C, and D. Saposin is an acronym for Sphingolipid Activator PrO[S]teINs. Each...
- The saposin domains refers to two evolutionally-conserved protein domains found in saposin and related proteins (SAPLIP). Saposins are small lysosomal...
- requires the activating protein Saposin C as well as negatively charged lipids for maximal catalytic activity. The role of Saposin C is not known; however, it...
- sections of the protein are removed; this relationship is found between saposin and swaposin. Fission and fusion occurs when partial proteins fuse to form...
- independent entity separate from its parent AP, is homologous to saposin and belongs to the saposin-like protein family (SAPLIP). Although the PSI is grouped...
- is not activated – the resulting disease is saposin B deficiency, which presents similar to MLD. Saposin B Deficiency is very rare, much more rare than...
- of the lung. Humans and animals born with a congenital absence of the saposin family SP-B experience intractable respiratory failure whereas those born...
- (2016-07-31). "Structure of Human Acid Sphingomyelinase Reveals the Role of the Saposin Domain in Activating Substrate Hydrolysis". Journal of Molecular Biology...
- Niemann–Pick disease Type A Type B Sulfatidosis Metachromatic leukodystrophy Saposin B deficiency Multiple sulfatase deficiency Mucopolysaccharidoses Type I...
- galactosylceramidase. In rare cases, it may be caused by a lack of active saposin A (a derivative of prosaposin). The buildup of unmetabolized lipids adversely...