-
Saccharopine is an
intermediate in the
metabolism of
amino acid lysine. It is a
precursor of
lysine in the alpha-aminoadipate
pathway which occurs in fungi...
-
Saccharopine dehydrogenase (SDH), also
named Saccharopine reductase, is an
enzyme involved in the
metabolism of the
amino acid lysine.
Saccharopine dehydrogenase...
- to
produce the
penultimate product,
saccharopine. The
final step of the
pathway in
fungi involves the
saccharopine dehydrogenase (SDH) (E.C 1.5.1.8) catalysed...
- In
molecular biology, the
protein domain Saccharopine dehydrogenase (SDH), also
named Saccharopine reductase, is an
enzyme involved in the metabolism...
- L-
saccharopine oxidase (EC 1.5.3.18, FAP2) is an
enzyme with
systematic name L-
saccharopine:oxygen
oxidoreductase (L-glutamate forming). This
enzyme catalyses...
-
catalyzes the
first two
steps in the
mammalian L-lysine
degradation via
saccharopine pathway within the mitochondria,
which is
thought to be the main metabolic...
-
whereas the D-enantiomer is a part of
certain antibiotics.
Through saccharopine and allysine,
lysine is
converted to α-aminoadipate,
which is then degraded...
- in
normal callus and
plant tissue as a
result of
arginine metabolism.
Saccharopine is an
intermediate in the
metabolism of
amino acid
lysine and occurs...
- with
glutamate by one
class of
saccharopine dehydrogenase yields saccharopine which is then
cleaved by a
second saccharopine dehydrogenase to
yield lysine...
- lysine→
Saccharopine Allysine α-Aminoadipic acid 2-Oxoadipic acid Glutaryl-CoA Glutaconyl-CoA Crotonyl-CoA β-Hydroxybutyryl-CoA leucine→ β-Hydroxy β-methylbutyric...