- element-binding
proteins (
SREBPs) are
transcription factors that bind to the
sterol regulatory element DNA
sequence TCACNCCAC.
Mammalian SREBPs are
encoded by the...
- PMID 27867498.
Osborne TF (August 2001). "CREating a SCAP-less
liver keeps SREBPs pinned in the ER
membrane and
prevents increased lipid synthesis in response...
-
regulatory element binding proteins (
SREBPs) and
mediates their transport from the ER to the
Golgi apparatus. The
SREBPs are then
proteolytically cleaved...
-
binding of SCAP to INSIG-1, a
membrane protein that
facilitates retention of
SREBPs in ER". Cell. 110 (4): 489–500. doi:10.1016/S0092-8674(02)00872-3. PMID 12202038...
-
protein SREBP (sterol
regulatory element-binding
protein 1 and 2). In the
presence of cholesterol,
SREBP is
bound to two
other proteins: SCAP (
SREBP cleavage-activating...
-
Michael Briggs,
purified the
Sterol Regulatory Element-Binding
Proteins (
SREBPs), a
family of membrane-bound
transcription factors.
Since 1993, Goldstein...
-
Michael Briggs purified the
sterol regulatory element binding proteins (
SREBPs).
Since 1993, Brown, Goldstein, and
their colleagues have
described the...
-
SREBPs have been
found to play a role with the
nutritional or
hormonal effects on the
lipogenic gene expression.
Overexpression of
SREBP-1a or
SREBP-1c...
- J,
Goldstein JL,
Brown MS (April 2007). "Sterol-regulated
transport of
SREBPs from
endoplasmic reticulum to Golgi:
Insig renders sorting signal in Scap...
-
encoding a ****tive
metalloprotease required for
intramembrane cleavage of
SREBPs".
Molecular Cell. 1 (1): 47–57. doi:10.1016/S1097-2765(00)80006-4. PMID 9659902...
