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Phosphoribosylaminoimidazolesuccinocarboxamide (
SAICAR) is an
intermediate in the
formation of purines. The
conversion of ATP, L-aspartate, and...
-
molecular biology, the
protein domain SAICAR synthase is an
enzyme which catalyses a
reaction to
create SAICAR. In enzymology, this
enzyme is also known...
- synthase. CAIR + L-Aspartate + ATP →
SAICAR + ADP + Pi The
eight is
catalyzed by
adenylosuccinate lyase.
SAICAR →
AICAR +
Fumarate The
products AICAR...
-
succinylpurines are the
dephosphorylated derivatives of
SAICA ribotide (
SAICAR) and
adenylosuccinate (S-AMP), the two
substrates of
adenylosuccinate lyase...
-
forming N-succinyl-5-aminoimidazole-4-carboxamide
ribonucleotide (
SAICAR).
SAICAR lyase removes the
carbon skeleton of the
added aspartate,
leaving the...
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makes AMP; ASL
cleaves adenylosuccinate into AMP and fumarate, and
cleaves SAICAR into
AICAR and fumarate.
Adenylosuccinate lyase is part of the β-elimination...
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ribonucleotide (
SAICAR).
Continuing down the pathway, the
removal of the
carbon skeleton of
aspartate by
SAICAR lyase results in...
- an
abundance of
SAICAR can
modify glucose absorption and
lactate production in
cancer cells. However, it has been
shown that
SAICAR binding also sufficiently...
-
Kanaujia SP;
Kanagaraj S;
Jeyakanthan J; et al. (February 2013). "Structure of
SAICAR synthetase from
Pyrococcus horikoshii OT3:
insights into
thermal stability"...
-
Ottoman advance over the
Timok river.
Although he
withdrew to the
fortress at
Saicar, the
Ottoman army
captured it on 7
August 1876
Gregorian (26 July 1876 Julian)...