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Romiplostim, sold
under the
brand name
Nplate among others, is a
fusion protein analog of thrombopoietin, a
hormone that
regulates platelet production...
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trials demonstrated romiplostim to be
effective in
treating chronic ITP,
especially in
relapsed post-splenectomy patients.
Romiplostim was
approved by the...
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antibodies against endogenous thrombopoietin or lead to thrombosis.
Romiplostim (trade name Nplate,
formerly AMG 531) was
found to be safe and effective...
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maturation of megakaryocytes. Some of them are
currently in
clinical use:
romiplostim, eltrombopag,
oprelvekin (a
recombinant interleukin 11) and thrombopoietin...
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selectively targeting effector memory T-cells to
treat psoriasis vulgaris.
Romiplostim: A
peptibody that
treats immune thrombocytopenia. Abatacept/Belatacept:...
- rise in the
hemoglobin level or a
person not
requiring a transfusion).
Romiplostim and
eltrombopag are
thrombopoeitin receptor agonists which act on megakaryocytes...
- inhibitors:
Agerafenib SCF (c-Kit) See here instead.
Thrombopoietin Agonists:
Eltrombopag Pegacaristim Promegapoietin Romiplostim Thrombopoietin (THPO, MGDF)...
- inhibitors:
Agerafenib SCF (c-Kit) See here instead.
Thrombopoietin Agonists:
Eltrombopag Pegacaristim Promegapoietin Romiplostim Thrombopoietin (THPO, MGDF)...
- inhibitors:
Agerafenib SCF (c-Kit) See here instead.
Thrombopoietin Agonists:
Eltrombopag Pegacaristim Promegapoietin Romiplostim Thrombopoietin (THPO, MGDF)...
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Neupogen (granulocyte colony-stimulating factor) for
neutropenia Nplate (
romiplostim) for
chronic immune thrombocytopenic purpura (FDA
approved 2008) Otezla...