-
Riociguat, sold
under the
brand name Adempas, is a
medication by
Bayer that is a
stimulator of
soluble guanylate cyclase (sGC). It is used to
treat two...
- bosentan, ambrisentan, macitentan, and sildenafil, tadalafil, selexipag,
riociguat. Lung
transplantation may be an
option in
severe cases. The frequency...
- "poppers")
Concomitant use of
soluble guanylyl cyclase stimulators, such as
riociguat Known hy****nsitivity to
sildenafil Sildenafil should not be used if...
- disease. PDE5
inhibitors are used
which cause dilation of
blood vessels.
Riociguat also
causes vasodilation.
Endothelin receptor antagonists cause vasodilation...
-
pulmonary hypertension, and
other diseases. The first-in-class
medication was
riociguat,
approved in 2013 for
pulmonary hypertension. They have also been investigated...
- (aflibercept),
Stivarga (regorafenib),
Xofigo (radium-223), and
Adempas (
riociguat).: 93 Top-selling
products as of 2014 included:
Kogenate (recombinant...
- Activators/stimulators:
Ataciguat BAY 41-2272 BAY 41-8543 BAY 60-4552 BI-703704
Cinaciguat (BAY 58-2667) GSK-2181236A
Praliciguat Riociguat Vericiguat Inhibitors: ODQ...
-
Bosentan C02KX02
Ambrisentan C02KX03
Sitaxentan C02KX04
Macitentan C02KX05
Riociguat C02KX06
Sotatercept C02KX52
Ambrisentan and
tadalafil C02KX54 Macitentan...
- Activators/stimulators:
Ataciguat BAY 41-2272 BAY 41-8543 BAY 60-4552 BI-703704
Cinaciguat (BAY 58-2667) GSK-2181236A
Praliciguat Riociguat Vericiguat Inhibitors: ODQ...
-
rationale for off-label use of
drugs approved for PAH. Currently, only
riociguat (a
stimulator of
soluble guanylate cyclase) is
approved for treatment...
