-
Rimonabant (also
known as SR141716;
trade names Acomplia, Zimulti) is an
anorectic antiobesity drug
approved in
Europe in 2006 but was
withdrawn worldwide...
-
receptor antagonists. The
first CBR
inverse agonist,
rimonabant, was
described in 1994.
Rimonabant blocks the CB1
receptor selectively and has been shown...
- depression, and
thoughts of
suicide in
patients treated with the now-withdrawn
rimonabant,
another CB1
antagonist that was also
under development by Sanofi-Aventis...
- at the CB1
cannabinoid receptor. AM-251 is
structurally very
close to
rimonabant; both are
biarylpyrazole cannabinoid receptor antagonists. In AM-251,...
-
drugs that were ever
approved by the FDA. Some of them (lumiracoxib,
rimonabant, tolrestat,
ximelagatran and ximelidine, for example) were
approved to...
- cannabis),
increased appetite. However, some
drugs in this
class such as
rimonabant were
withdrawn or
ceased development to
concerns about mental health and...
-
cannabinoid receptor CB1. It is
derived from the
widely used CB1
antagonist rimonabant, and has
similar potency and
selectivity for the CB1 receptor, but has...
- The
antihypertensive effect of
spilanthol was
blocked by CB1
antagonist rimonabant and TRPV1
antagonist capsazepine,
suggesting spilanthol mediates some...
-
developed for the
treatment of obesity.
Other cannabinoid antagonists such as
rimonabant have been
marketed for this application, but have
subsequently been withdrawn...
-
Federal Analogue Act
Hexahydrocannabivarin Medical cannabis Parahexyl Rimonabant (synthetic CB1 antagonist)
Tetrahydrocannabiorcol (Δ9-THCC, (C1)-Δ9-THC)...
