Definition of Rhodanese. Meaning of Rhodanese. Synonyms of Rhodanese

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Definition of Rhodanese

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Meaning of Rhodanese from wikipedia

- Rhodanese is a mitochondrial enzyme that detoxifies cyanide (CN−) by converting it to thiocyanate (SCN−, also known as "rhodanate"). In enzymatology,...
- Malekhusseini A, Akrami F, Ebrahimnejad H (2006). "Cyanide-metabolizing enzyme rhodanese in human tissues: Comparison with domestic animals". Comparative Clinical...
- exception is cyanide, which can be metabolized by the liver. The enzyme rhodanese converts the cyanide into the much less toxic thiocyanate. This process...
- is by enzymatic conversion to thiocyanate by the mitochondrial enzyme rhodanese. Thiocyanate is a relatively non-toxic molecule and is excreted by the...
- is however still used for the treatment of a hypertensive emergency. Rhodanese catalyzes the reaction of sodium nitroprusside (like other cyanides) with...
- identified. The encoded cytoplasmic protein is a member of the rhodanese family but is not rhodanese itself, which is found only in mitochondria. MPST protein...
- contained low concentrations of beta-glucosidases and high concentrations of rhodanese, which converts HCN to the less toxic thiocyanate. Later, however, it...
- cyanide produced to be detoxified within the body to thiocyanate (the rhodanese pathway). It also allows more of the acetonitrile to be excreted unchanged...
- (eight per ring). It has been shown to fold the mitochondrial protein rhodanese; however, no natural substrates have yet been identified. Group II chaperonins...
- small quantities. It is metabolized by rhodanese, a live enzyme at a rate of approximately 17 μg/kg·min. Rhodanese catalyzes the irreversible reaction forming...