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Rhodanese is a
mitochondrial enzyme that
detoxifies cyanide (CN−) by
converting it to
thiocyanate (SCN−, also
known as "rhodanate"). In enzymatology,...
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Malekhusseini A,
Akrami F,
Ebrahimnejad H (2006). "Cyanide-metabolizing
enzyme rhodanese in
human tissues:
Comparison with
domestic animals".
Comparative Clinical...
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exception is cyanide,
which can be
metabolized by the liver. The
enzyme rhodanese converts the
cyanide into the much less
toxic thiocyanate. This process...
- is by
enzymatic conversion to
thiocyanate by the
mitochondrial enzyme rhodanese.
Thiocyanate is a
relatively non-toxic
molecule and is
excreted by the...
- identified. The
encoded cytoplasmic protein is a
member of the
rhodanese family but is not
rhodanese itself,
which is
found only in mitochondria. MPST protein...
-
contained low
concentrations of beta-glucosidases and high
concentrations of
rhodanese,
which converts HCN to the less
toxic thiocyanate. Later, however, it...
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cyanide produced to be
detoxified within the body to
thiocyanate (the
rhodanese pathway). It also
allows more of the
acetonitrile to be
excreted unchanged...
-
small quantities. It is
metabolized by
rhodanese, a live
enzyme at a rate of
approximately 17 μg/kg·min.
Rhodanese catalyzes the
irreversible reaction forming...
- is
however still used for the
treatment of a
hypertensive emergency.
Rhodanese catalyzes the
reaction of
sodium nitroprusside (like
other cyanides) with...
-
reaction with a sulfur-donor such as thiosulfate,
catalysed by the
enzyme rhodanese. In the
absence of
sufficient thiosulfate,
cyanide ions can
quickly reach...
