-
Rho family of
GTPases is a
family of
small (~21 kDa)
signaling G proteins, and is a
subfamily of the Ras superfamily. The
members of the
Rho GTPase family...
-
GTPases are a
large family of
hydrolase enzymes that bind to the
nucleotide guanosine triphosphate (GTP) and
hydrolyze it to
guanosine diphosphate (GDP)...
-
Transforming protein RhoA, also
known as Ras
homolog family member A (
RhoA), is a
small GTPase protein in the
Rho family of
GTPases that in
humans is encoded...
-
activate Rac1, a
RhoGTPase, in
addition to its role as a GEF for Ras. SOS is
therefore a link
between the Ras-Family and
Rho-Family
GTPase signaling pathways...
- is a
GTPase-activating protein. Furthermore, YopE is a
protein domain that is a
Rho GTPase-activating
protein (GAP),
which targets small GTPases such...
-
Rho GTPase activating protein 21 is a
protein that in
humans is
encoded by the ARHGAP21 gene. ARHGAP21
functions preferentially as a
GTPase-activating...
-
RhoC (Ras
homolog gene family,
member C) is a
small (~21 kDa)
signaling G
protein (more
specifically a
GTPase), and is a
member of the Rac
subfamily of...
-
Murakoshi et al. in 2011
implicated the
Rho GTPases RhoA and Cdc42 in
dendritic spine morphogenesis. Both
GTPases were
quickly activated in
single dendritic...
- G protein-coupled receptors,
which activate GTPases of the
Rho family (e.g. Cdc42, Rac) via G proteins.
Rho GTPases are able to
activate WASp
which in turn...
- of cell
signalling in
animal cells, in
particular the role of
Rho and Ras
small GTPases in
regulating a
variety of
cellular functions such as proliferation...
