-
Rhizoxin is an
antimitotic agent with anti-tumor activity. It is
isolated from the
fungus Rhizopus microsporus which causes rice
seedling blight. Rhizoxin...
-
endosymbiont Paraburkholderia rhizoxinica that
produces the
antitumor drug
rhizoxin.
Certain strains of
Rhizopus microsporus use
agricultural rice as a host...
- It
inhibits the ****embly of
microtubules by
binding to
tubulin at the
rhizoxin binding site. The
maytansine binding site and
binding mode has been characterized...
- oligosporus. R.
microsporus produces several potentially toxic metabolites,
rhizoxin and
rhizonins A and B, but it
appears the
domestication and
mutation of...
- it
inhibits the ****embly of
microtubules by
binding to
tubulin (at the
rhizoxin binding site). The
monoclonal antibody binds specifically to a structure...
-
found to
produce rhizoxin, an
inhibitor of
mitosis originally thought to be
produced by R.
microsporus itself. The
production of
rhizoxin by Burkholderia...
-
vector –
retrovirus – RevM10 gene –
rhabdoid tumor –
rhabdomyosarcoma –
rhizoxin –
ribavirin –
ribonucleotide reductase inhibitor –
rifampin – risedronate...
- Stonehouse,
Jeffery P. (2002). "A
concise enantioselective total synthesis of
rhizoxin D".
Tetrahedron Lett. 43 (3): 493–497. doi:10.1016/S0040-4039(01)02154-2...
-
Epothilone A, the CD-Subunit of spongistatins, and the C10-C20
Subunit of
rhizoxin A, The Keck
allylation has also been
utilized to form
substituted tetrahydropyrans...
-
Jaspamide and
Geodiamolides and macrolides,
namely Zearalenone, Rifamycin-S,
Rhizoxin and Rapamycin. Rao is the
pioneer of
Chiral synthesis and
technology in...
