- penetrance.
Inherited forms of
retinoblastomas are more
likely to be bilateral. In addition,
inherited uni- or
bilateral retinoblastomas may be ****ociated with...
- The
retinoblastoma protein (protein name
abbreviated Rb or pRb; gene name
abbreviated Rb, RB or RB1) is a
tumor suppressor protein that is dysfunctional...
-
Trilateral retinoblastoma (TRb) is a
malignant midline primitive neuroectodermal tumor occurring in
patients with
inherited uni- or
bilateral retinoblastoma. In...
-
toward malignancy. Thus, in the case of
common blastomas, such as
retinoblastomas, a
practitioner may go
directly into treatment. However, in the case...
- of
retinoblastoma, a
malignant tumor of the
retina that
occurs both as an
inherited disease and sporadically. He
noted that
inherited retinoblastoma occurs...
- differentiation. In
addition to
being a
characteristic finding in
retinoblastomas, Flexner–Wintersteiner
rosettes may also be
found in pinealoblastomas...
- the
retinoblastoma tumor suppressor protein.
Alfred Knudson, a
pediatrician and
cancer geneticist,
proposed that in
order to
develop retinoblastoma, two...
-
Retinoblastoma-like
protein 2 is a
protein that in
humans is
encoded by the RBL2 gene. RBL2 is one of
three retinoblastoma proteins encoded in the human...
-
consists of
three proteins: RB –
Retinoblastoma protein p107 –
Retinoblastoma-like
protein 1 p130 –
Retinoblastoma-like
protein 2 They play
crucial roles...
-
transcript was the
retinoblastoma gene.
Subsequent work
identified point mutations that
inactivated the gene in
retinoblastomas and
other tumors. Dryja’s...
