-
Retinoblastoma (Rb) is a rare form of
cancer that
rapidly develops from the
immature cells of a retina, the light-detecting
tissue of the eye. It is the...
- The
retinoblastoma protein (protein name
abbreviated Rb or pRb; gene name
abbreviated Rb, RB or RB1) is a
tumor suppressor protein that is dysfunctional...
- the
retinoblastoma tumor suppressor protein.
Alfred Knudson, a
pediatrician and
cancer geneticist,
proposed that in
order to
develop retinoblastoma, two...
-
lentis (PFV/PHPV),
retinoblastoma, and
retrolental fibroplasia.
Because of the
potentially life-threatening
nature of
retinoblastoma, a cancer, that condition...
-
Trilateral retinoblastoma (TRb) is a
malignant midline primitive neuroectodermal tumor occurring in
patients with
inherited uni- or
bilateral retinoblastoma. In...
- of
retinoblastoma, a
malignant tumor of the
retina that
occurs both as an
inherited disease and sporadically. He
noted that
inherited retinoblastoma occurs...
-
often called blasts.
Examples are nephroblastoma, medulloblastoma, and
retinoblastoma. The
suffix -blastoma is used to
imply a
tumor of primitive, incompletely...
- or
bilateral retinoblastoma. When
retinoblastoma patients present with
pineoblastoma this is
characterized as "trilateral
retinoblastoma". Up to 5% of...
-
concrete structures Retinoblastoma, a
childhood cancer of the eyes
caused by a
mutation in the
retinoblastoma protein Retinoblastoma protein, a
tumor suppressor...
- cancer.
During this transition, G1
cyclin D-Cdk4/6
dimer phosphorylates retinoblastoma releasing transcription factor E2F,
which then
drives the transition...
