-
Reticuline is an
alkaloid found in
opium and a
variety of
plants including Lindera aggregata,
Annona squamosa, and
Ocotea fasciculata (also
known as Ocotea...
- The
conversion of (S) -norcoclaurin to (S) -
reticuline is one of the key points,
since from (S) -
reticuline morphine can be
formed through the morphinan...
- of
opium poppy. Its
biosynthetic precursor is the
alkaloid (R)-
reticuline. (R)-
Reticuline is
converted to
salutaridine by the
enzyme salutaridine synthase...
-
those from
which opium is derived, as well as in actaea. For instance,
reticuline has been
isolated from
Annona reticulata. Over 2500
biologically active...
- The
addition of
another methyl group transforms this
compound into
reticuline. Notably,
biosynthesis of
sanguinarine up to this
point is
virtually identical...
- (R)-
reticuline +
NADPH + H+ + O2 ⇌ {\displaystyle \rightleftharpoons }
salutaridine + NADP+ + 2 H2O The 4
substrates of this
enzyme are (R)-
reticuline, NADPH...
-
cyclization to the
aromatic ring
occurs by
virtue of the
phenolic group.
Reticuline is the
immediate precursor of
protoberberine alkaloids in plants. Berberine...
- is
biosynthetically related to salutaridine, oripavine,
morphine and
reticuline. In 2012
there was an
amounted 146,000
kilograms of
thebaine produced...
- (NADPH) (EC 1.5.1.27) is an
enzyme that
catalyzes the
chemical reaction (R)-
reticuline + NADP+ ⇌ {\displaystyle \rightleftharpoons } 1,2-dehydroreticulinium...
-
Dopamine +
DOPAL → (S)-norlaudanosoline →→→ (S)-
reticuline → 1,2-dehydroreticulinium → (R)-
reticuline →
salutaridine →
salutaridinol →
thebaine → neopinone...
