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Resolvins are
specialized pro-resolving
mediators (SPMs)
derived from omega-3
fatty acids,
primarily eicosapentaenoic acid (EPA) and
docosahexaenoic acid...
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orchestrating the
resolution of inflammation.
Prominent members include the
resolvins and protectins. SPM join the long list of
other physiological agents which...
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prominently the prostaglandins, thromboxanes, leukotrienes, lipoxins,
resolvins, and eoxins. For each subfamily,
there is the
potential to have at least...
- but also many
other agents including the
docosanoids resolvin D1,
resolvin D2, and 17R-
resolvin D1 (see
specialized pro-resolving mediators; oligopeptides...
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dramatically reduce inflammation through conversion within the body to
resolvins, with
beneficial effects for the
cardiovascular system and arthritis....
- anti-inflammatory
specialized proresolving mediators, i.e. lipoxins,
resolvins, maresins, and
neuroprotectins Downregulation of pro-inflammatory molecules...
-
cyclooxygenase 2-derived
resolvin E
series metabolites of the
omega 3
fatty acid,
eicosapentaenoic acid;
certain 15-lipoxygenase-derived
resolvin D
series metabolites...
- four
resolvins of T
series and
three of D
series (RvT1, RvT2, RvT3, RvT4, RvD1n-3, RvD2n-3, and RvD5n-3 (do not
confuse with D
series resolvins derived...
-
series resolvins (see
Resolvin §
Resolvin Es) and of
docosahexaenoic acid to D
series resolvins (see
Resolvin §
Resolvin Ds).
These resolvins are also...
-
NAGly was not
shown to be a GPR18
agonist in rat
sympathetic neurons.
Resolvin D2 (RvD2), a
member of the
specialized proresolving mediators (SPM) class...