-
Recombinases are
genetic recombination enzymes. DNA
recombinases are
widely used in
multicellular organisms to mani****te the
structure of genomes, and...
- all of
these belong to
either of two families,
tyrosine recombinases (YR) and
serine recombinases (SR),
depending on
their mechanism.
These two families...
- Cre
recombinase is a
tyrosine recombinase enzyme derived from the P1 bacteriophage. The
enzyme uses a
topoisomerase I-like
mechanism to
carry out site...
- protein, much like Cre, is a
tyrosine family site-specific
recombinase. This
family of
recombinases performs its
function via a type IB
topoisomerase mechanism...
-
protein structures and
reaction mechanisms.
Unlike tyrosine recombinases,
serine recombinases are
highly modular, as was
first hinted by
biochemical studies...
-
three core
enzymes – a
recombinase, a single-stranded DNA-binding
protein (SSB) and strand-displacing polymerase.
Recombinases are
capable of pairing...
-
majority of T cells. The
process of V(D)J
recombination is
mediated by VDJ
recombinase,
which is a
diverse collection of enzymes. The key
enzymes involved are...
- Hin
recombinase is a 21kD
protein composed of 198
amino acids that is
found in the
bacteria Salmonella. Hin
belongs to the
serine recombinase family (B2)...
- has been
previously established that
coexpression of both Cre and Flp
recombinases catalyzes the
exchange of
sequences flanked by
single loxP and FRT sites...
-
sites for the
catalyzing action of
special enzymes called recombinases. Cre, or
cyclic recombinase, is one such enzyme. Site-specific
recombination is, thus...
