-
Rasagiline, sold
under the
brand name
Azilect among others, is a
medication which is used in the
treatment of Parkinson's disease. It is used as a monotherapy...
- imipramine, desipramine),
monoamine oxidase inhibitors (MAOIs) (e.g.,
rasagiline),
serotonin antagonists and
reuptake inhibitors (SARIs) (e.g., nefazodone)...
- MAO-B
inhibitor and
antiparkinsonian agent rasagiline ((R)-N-propargyl-1-aminoindane). In
contrast to
rasagiline, it
lacks significant monoamine oxidase...
-
pharmacologically active and is an
active metabolite of the
antiparkinsonian agent rasagiline.
Through its (R)-enantiomer (R)-1-aminoindane, 1-aminoindane has pharmacological...
- disease.
There is
evidence that
selegiline may be more
effective than
rasagiline in the
treatment of Parkinson's disease. This may be due to pharmacological...
- B
propargyl amine inhibitor rasagiline (N-propargyl-1-R-aminoindan, Azilect((R))). The oral
bioavailability of
rasagiline is 35%, it
reaches T(max) after...
- Parkinson's disease. It was
developed from
structural modification of
rasagiline. The drug acts as a
reversible acetylcholinesterase and butyrylcholinesterase...
-
amphetamine metabolites or have ****ociated
cardiovascular effects, such as
rasagiline, have also been
developed and introduced.
Because selegiline metabolizes...
- Parkinson's
disease (PD), and
several anti-apoptotic PD drugs, such as
rasagiline,
function by
preventing the
nuclear translocation of GAPDH. It is proposed...
-
moclobemide and clorgyline, and MAOB
selective agents such as
selegiline and
rasagiline, as well as the
harmala alkaloids like harmine, harmaline, tetrahydroharmine...