-
Radicicol, also
known as monorden, is a
natural product that
binds to Hsp90 (Heat
Shock Protein 90) and
alters its function. HSP90
client proteins play...
- (Vitamin B6)
Pyrimidine Pyrrolysine Pyruvic acid
Quinidine Quinine Quinone Radicicol Raffinose Relaxin Renin Retinene Retinol (Vitamin A)
Reverse transcriptase...
- (a
calcineurin inhibitor) and
sirolimus (rapamycin) (a mTOR inhibitor)
Radicicol and the
pochonin family (HSP90 inhibitors) The
cholesterol lowering agent...
- (IPI 504, a
hydroquinone hydrochloride salt
derivative of 17-AAG) and
radicicol as well as
semisynthetic derivatives 17-N-Allylamino-17-demethoxygeldanamycin...
-
pyruvate dehydrogenase kinase isoforms by AZD7545, dichloroacetate, and
radicicol". Structure. 15 (8): 992–1004. doi:10.1016/j.str.2007.07.001. PMC 2871385...
- this
section of Hsp90
include the
antibiotics geldanamycin, herbimycin,
radicicol, deguelin, derrubone, macbecin, and beta-lactams. The protein-binding...
-
inhibitors are AZD7545 and
dichloroacetate which both bind to PDK1, and
Radicicol which binds to PDK3.
Mutations in the PDK3 gene are a rare
cause of X-linked...
- ****van, W.; Stensgard, B.; Toft, D.; Neckers, L. M. (1998). "Antibiotic
radicicol binds to the N-terminal
domain of Hsp90 and
shares important biologic...
-
resorcylic acid lactones, 'monocillin IV' (1), 'monocillin II' (5) and
radicicol (6)
which were also
isolated and identified,
where compounds 4–6 show...
-
Structure of the N-domain of the ER Hsp90
chaperone GRP94 in
complex with
Radicicol 1qye:
Crystal Structure of the N-domain of the ER Hsp90
chaperone GRP94...
