- 5α-
Reductase 2
deficiency (5αR2D) is an
autosomal recessive condition caused by a
mutation in SRD5A2, a gene
encoding the
enzyme 5α-
reductase type 2 (5αR2)...
- 5α-
Reductases, also
known as 3-oxo-5α-steroid 4-dehydrogenases, are
enzymes involved in
steroid metabolism. They parti****te in
three metabolic pathways:...
- above.
Common names are also
sometimes formed as "acceptor
reductase", such as NAD+
reductase. "Donor oxidase" is a
special case
where O2 is the acceptor...
- 5α-
Reductase inhibitors (5-ARIs), also
known as
dihydrotestosterone (DHT) blockers, are a
class of
medications with
antiandrogenic effects which are used...
-
Statins (or HMG-CoA
reductase inhibitors) are a
class of
medications that
reduce illness and
mortality in
people who are at high risk of cardiovascular...
- HMG-CoA
reductase (3-hydroxy-3-methyl-glutaryl-coenzyme A
reductase,
official symbol HMGCR) is the rate-controlling
enzyme (NADH-dependent, EC 1.1.1.88;...
- well as the
production of
sebum and body hair composition. The
enzyme 5α-
reductase catalyzes the
formation of DHT from
testosterone in
certain tissues including...
-
Dihydrofolate reductase, or DHFR, is an
enzyme that
reduces dihydrofolic acid to
tetrahydrofolic acid,
using NADPH as an
electron donor,
which can be...
-
reductase (MTHFR) is the rate-limiting
enzyme in the
methyl cycle, and it is
encoded by the
MTHFR gene.
Methylenetetrahydrofolate reductase catalyzes...
-
exposure by
acting specifically on hair follicles.
Finasteride is a 5α-
reductase inhibitor and
therefore an antiandrogen. It
works by
decreasing the production...