-
treatments for
cancer based on
interactions with G-
quadruplexes.
Early evidence for the
formation of G-
quadruplexes in vivo in
cells was
established by isolating...
-
polymerases relative to the DNA
strand in a non-arbitrary manner. G-
quadruplexes, also
known as G4 DNA are
secondary structures found in
nucleic acids...
-
functions remain unclear. G-
quadruplexes are four-stranded DNA
structures formed by guanine-rich sequences. G-
quadruplexes can form in telomeres, oncogene...
- non-coding
genetic elements,
particularly four-stranded
structures called G-
quadruplexes. His work on the
intervention of
nucleic acid
function using small molecules...
-
including the
group I intron, the
group II intron, and the ribosome.
Quadruplexes Although the
major groove of
standard A-form RNA is
fairly narrow and...
-
secondary structures of
single stranded DNA and RNA G-rich
called G-
quadruplexes (G4-DNA and G4-RNA).
Evidence exists for both in
vitro and in vivo formation...
-
Parkinson GN, Lee MP,
Neidle S (June 2002). "Crystal
structure of
parallel quadruplexes from
human telomeric DNA". Nature. 417 (6891): 876–80. Bibcode:2002Natur...
-
Antonella Virgilio &
Luciano Mayol (2005). "Structural
studies on LNA
quadruplexes". Nucleosides,
Nucleotides and
Nucleic Acids. 24 (5–7): 795–800. doi:10...
- "Innate
immune suppression by SARS-CoV-2 mRNA vaccinations: The role of G-
quadruplexes, exosomes, and MicroRNAs". Food and
Chemical Toxicology. 164: 113008...
- in
nucleic acid
structure and recognition, and the
research topic of
quadruplexes.
Stephen Neidle was born in
London and
educated at
Hendon County Grammar...
