-
pathway of queuosine. The
enzyme from
Escherichia coli can also
convert 6-
pyruvoyl-5,6,7,8-tetrahydropterin and
sepiapterin to 6-carboxy-5,6,7,8-tetrahydropterin...
-
catalyzes the
transformation of 7,8-dihydroneopterin
triphosphate into 6-
pyruvoyl tetrahydropterin synthase. The
kinetic values for this
enzyme are KM =...
- 2-dihydroxy-3′-triphosphooxypropyl]-7,8-dihydropterin triphosphate-lyase (6-
pyruvoyl-5,6,7,8-tetrahydropterin-forming).
Other names in
common use
include 2-amino-4-oxo-6-[(1S...
-
reaction also
splits the chain, but
results in a
pyruvoyl group at the new N-terminus. This
pyruvoyl group may be used as a
covalently attached catalytic...
-
which show
little sequence similarity either to each other, or to
other pyruvoyl-dependent
amino acid decarboxylases:
class I
enzymes found in bacteria...
- Thöny B, Blau N (1997). "Mutations in the GTP
cyclohydrolase I and 6-
pyruvoyl-tetrahydropterin
synthase genes". Hum. Mutat. 10 (1): 11–20. doi:10...
- 6PPH4(2'-oxo) reductase, 6-
pyruvoyl tetrahydropterin (2'-oxo)reductase, 6-
pyruvoyl-tetrahydropterin 2'-reductase, and
pyruvoyl-tetrahydropterin reductase...
- biosynthesis. It is
transformed by 6-pyruvoyltetrahydropterin
synthase into 6-
pyruvoyl-tetrahydropterin. It is also used in the Queuosine/Archeosine Pathway.[citation...
-
common HDC,
while gram-positive
bacteria employ an
evolutionarily unrelated pyruvoyl-dependent HDC. In humans,
histidine decarboxylase is
encoded by the HDC...
- to 6-
pyruvoyl-5,6,7,8-tetrahydropterin by 6-pyruvoyltetrahydropterin synthase,
which removes the
phosphate and
produces the ****tone (
pyruvoyl) substituent...
