-
PtdIns(4,5)P2
forming phosphatidylinositol (3,4,5)-trisphosphate (
PtdIns(3,4,5)P3) and
PtdIns(4,5)P2 can be
converted from
PtdIns4P.
PtdIns4P,
PtdIns(3...
- 3,4-bisphosphate, also
known as
PtdIns(3,4)P2 or PI(3,4)P2
Phosphatidylinositol 3,5-bisphosphate, also
known as
PtdIns(3,5)P2 or PI(3,5)P2 Phosphatidylinositol...
-
Phosphatidylinositol (3,4,5)-trisphosphate (
PtdIns(3,4,5)P3),
abbreviated PIP3, is the
product of the
class I
phosphoinositide 3-kinases' (PI 3-kinases)...
- that
PtdIns(3,5)P2 is
reverted to
PtdIns3P soon
after its synthesis. In
mammalian cells,
PtdIns(3,5)P2 is
synthesized from and
turned over to
PtdIns3P...
- 3-phosphorylated
phosphoinositides that are
produced by PI3Ks (
PtdIns3P,
PtdIns(3,4)P2,
PtdIns(3,5)P2, and
PtdIns(3,4,5)P3)
function in a
mechanism by
which an ****orted...
-
using PtdIns(4)P as a substrate, in fact
required PtdIns(5)P as a
substrate to
produce PtdIns(4,5)P2.
Further research demonstrated that
PtdIns(5)P is...
- 4)-bisphosphate (
PtdIns(3,4)P2) is a
minor phospholipid component of cell membranes, yet an
important second messenger. The
generation of
PtdIns(3,4)P2 at the...
- FYVE
domains are more
specific for
PtdIns3P. ENTH
domains bind
PtdIns(3,4)P2 or
PtdIns(4,5)P2. ANTH
domain binds PtdIns(4,5)P2.
Proteins from ERM (ezrin/radixin/moesin)...
- 3-phosphate (
PtdIns(3)P) on the
surface of the phagop****. The
generated PtdIns(3)P is used as a
docking point for
proteins harboring a
PtdIns(3)P binding...
-
activating CREB,
inhibiting p27,
localizing FOXO in the cytoplasm,
activating PtdIns-3ps, and
activating mTOR
which can
affect transcription of p70 or 4EBP1...