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clinical and
therapeutic applications for
psychedelic and, more broadly,
psychoplastogenic drugs.
MindMed was
founded in May 2019 by
Stephen Hurst and Jamon...
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strictly seem to be true. Conversely, 6-MeO-isoDMT has
comparable psychoplastogenic potency and
effects compared to 5-MeO-DMT.
These effects are blocked...
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serotonin 5-HT2
receptor agonist similarly to LSD and to
produce psychoplastogenic effects. Like LSD, the drug is
known to be a
highly potent serotonin...
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receptor partial agonist, as well as
acting at
other targets, with
psychoplastogenic and antidepressant-like
effects in animals. 2-Bromo-LSD was found...
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expression of
genes related to
synaptic plasticity and
hence to have
psychoplastogenic effects. This is in part due to
binding to brain-derived neurotrophic...
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addition to its
psychedelic effects,
psilocin has been
found to
produce psychoplastogenic effects in animals,
including dendritogenesis, spinogenesis, and synaptogenesis...
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mechanism of
action of DLX-159 has yet to be disclosed. The drug
shows psychoplastogenic effects in
vitro and ex vivo.
These effects are
blocked by the serotonin...
- non-hallucinogenic. On the
other hand, 5-MeO-isoDMT has
comparable psychoplastogenic potency and
effects compared to the
psychedelic 5-MeO-DMT.
These effects...
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psychedelics may also
produce a
variety of
other effects,
including psychoplastogenic (i.e., neuroplasticity-enhancing), antidepressant, anxiolytic, empathy-enhancing...
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retains significant activity at the
serotonin 5-HT2
receptors and
shows psychoplastogenic effects comparable to
those of
serotonergic psychedelics in preclinical...